Corylifol A
CAS No. 775351-88-7
Corylifol A ( Corylifol-A; Corylinin )
产品货号. M19098 CAS No. 775351-88-7
Corylifol A displays cytotoxic activity against HepG2 and Hep3B hepatocellular carcinoma cell lines, with IC50 values of 4.6 and 13.5 ug/ml, respectively.
纯度: 98%
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
规格 | 价格/人民币 | 库存 | 数量 |
5MG | ¥786 | 有现货 |
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10MG | ¥1256 | 有现货 |
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25MG | ¥2122 | 有现货 |
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50MG | ¥3151 | 有现货 |
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100MG | ¥4641 | 有现货 |
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200MG | 获取报价 | 有现货 |
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500MG | 获取报价 | 有现货 |
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1G | 获取报价 | 有现货 |
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生物学信息
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产品名称Corylifol A
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注意事项本公司产品仅用于科研实验,不得用于人体或动物的临床与诊断
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产品简述Corylifol A displays cytotoxic activity against HepG2 and Hep3B hepatocellular carcinoma cell lines, with IC50 values of 4.6 and 13.5 ug/ml, respectively.
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产品描述Corylifol A displays cytotoxic activity against HepG2 and Hep3B hepatocellular carcinoma cell lines, with IC50 values of 4.6 and 13.5 ug/ml, respectively. Corylifol A and Biochanin A can be the potential uncouplers of neuronal nitric oxide synthase-postsynaptic density protein-95. Corylifol A and bavachin are strong inhibitors of UDP-glucuronosyltransferase 1A1 (UGT1A1) with the inhibition kinetic parameters (Ki) values lower than 1 uM.Corylifol A and bakuchiol are naturally occurring potent inhibitors of hCE2, with low Ki values ranging from 0.62uM to 3.89 uM. Corylifol A shows an inhibitory effect on IL-6-induced STAT3 promoter activity in Hep3B cells with IC50 values of 0.81 ± 0.15 uμ, it also inhibits STAT3 phosphorylation induced by IL-6 in Hep3B cells, suggests that corylifol A has antiinflammatory activity.
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同义词Corylifol-A; Corylinin
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通路Others
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靶点Other Targets
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受体UGT1A1;hCE2
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研究领域Others-Field
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适应症——
化学信息
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CAS Number775351-88-7
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分子量390.47
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分子式C25H26O4
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纯度98%
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溶解度DMSO : ≥ 15.4 mg/mL; 39.44 mM
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SMILESCC(=CCCC(=CCC1=C(C=CC(=C1)C2=COC3=C(C2=O)C=CC(=C3)O)O)C)C
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化学全称——
运输与储存
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储存条件(-20℃)
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运输条件With Ice Pack
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稳定性≥ 2 years
参考文献
产品手册
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